A linha 321 é identificada pela cor laranja e opera como linha alimentadora, conectando o Terminal Centenário ao Terminal Vila Oficinas. O itinerário atravessa bairros como Cristo Rei e Jardim Botânico, passando por vias principais dessas regiões.
O maior número de horários ocorre no início da manhã e no final da tarde, enquanto o menor número de partidas é observado durante a madrugada, embora a linha opere até 00:30.
Horários partindo do Terminal Vila Oficinas
Dias Úteis: 05:11, 05:47, 06:25, 06:45, 07:05,
07:25, 07:45, 08:05, 08:25, 09:03, 09:39, 10:15, 10:51, 11:28, 12:06, 12:42,
13:17, 13:53, 14:29, 15:05, 15:40, 16:15, 16:35, 16:55, 17:15, 17:35, 17:55,
18:15, 18:35, 18:55, 19:15, 19:35, 19:55, 20:31, 21:07, 21:43, 22:19, 22:55,
23:30, 00:00, 00:30
Sábados: 05:53, 06:29, 07:05, 07:41, 08:17, 08:53,
09:29, 10:05, 10:41, 11:17, 11:53, 12:29, 13:05, 13:41, 14:17, 14:53, 15:29,
16:05, 16:41, 17:17, 17:53, 18:29, 19:05, 19:41, 20:17, 20:53, 21:29, 22:05,
22:41, 23:17, 23:50, 00:20
Domingos: 05:53, 06:29, 07:05, 07:41, 08:17, 08:53, 09:29, 10:05, 10:41, 11:17, 11:53, 12:29, 13:05, 13:41, 14:17, 14:53, 15:29, 16:05, 16:41, 17:17, 17:53, 18:29, 19:05, 19:41, 20:17, 20:53, 21:29, 22:05, 22:41, 23:17, 23:50, 00:20
Horários partindo do Terminal Centenário
Dias Úteis: 04:53, 05:29, 06:05, 06:25, 06:45,
07:05, 07:25, 07:45, 08:05, 08:25, 08:45, 09:21, 09:57, 10:33, 11:10, 11:48,
12:25, 12:59, 13:35, 14:11, 14:47, 15:23, 15:58, 16:35, 16:55, 17:15, 17:35,
17:55, 18:15, 18:35, 18:55, 19:15, 19:35, 20:13, 20:49, 21:25, 22:02, 22:37,
23:13, 23:45, 00:15
Sábados: 05:35, 06:11, 06:47, 07:23, 07:59, 08:35,
09:11, 09:47, 10:23, 10:59, 11:35, 12:11, 12:47, 13:23, 13:59, 14:35, 15:11,
15:47, 16:23, 16:59, 17:35, 18:11, 18:47, 19:23, 19:59, 20:35, 21:11, 21:47,
22:23, 22:59, 23:35, 00:05
Domingos: 05:35, 06:11, 06:47, 07:23, 07:59, 08:35, 09:11, 09:47, 10:23, 10:59, 11:35, 12:11, 12:47, 13:23, 13:59, 14:35, 15:11, 15:47, 16:23, 16:59, 17:35, 18:11, 18:47, 19:23, 19:59, 20:35, 21:11, 21:47, 22:23, 22:59, 23:35, 00:05
Primeiro horário de
saída: 04:53 (Terminal Centenário)
Último horário de
saída: 00:30 (Terminal Vila Oficinas)
